User profiles for N. D. Lewis

Nicola Denzey Lewis

Margo L. Goldsmith Chair of Women's Studies in Religion, Claremont Graduate University
Verified email at cgu.edu
Cited by 506

[PDF][PDF] Epidemiology and impact of ciguatera in the Pacific: a review

ND Lewis - Marine fisheries review, 1986 - researchgate.net
For inhabitants ofthe Pacific Islands, the mean reported incidence of ciguaterafrom 1979 to
1983 was 971100, 000. As a health problem, ciguatera also appears to be increasing on …

[HTML][HTML] A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties

K Dooley, RE McConnell, K Xu, ND Lewis, S Haupt… - Molecular Therapy, 2021 - cell.com
Extracellular vesicles (EVs) are an important intercellular communication system facilitating
the transfer of macromolecules between cells. Delivery of exogenous cargo tethered to the …

Climate variability and change and their potential health effects in small island states: information for adaptation planning in the health sector

KL Ebi, ND Lewis, C Corvalan - Environmental health …, 2006 - ehp.niehs.nih.gov
Small island states are likely the countries most vulnerable to climate variability and long-term
climate change. Climate models suggest that small island states will experience warmer …

l-Arginine Availability Regulates Inducible Nitric Oxide Synthase-Dependent Host Defense against Helicobacter pylori

R Chaturvedi, M Asim, ND Lewis… - Infection and …, 2007 - Am Soc Microbiol
Helicobacter pylori infection of the stomach causes an active immune response that includes
stimulation of inducible nitric oxide (NO) synthase (iNOS) expression. Although NO can kill …

Arginase II restricts host defense to Helicobacter pylori by attenuating inducible nitric oxide synthase translation in macrophages

ND Lewis, M Asim, DP Barry, K Singh… - The Journal of …, 2010 - journals.aai.org
Helicobacter pylori infection of the stomach causes peptic ulcer disease and gastric cancer.
Despite eliciting a vigorous immune response, the bacterium persists for the life of the host. …

Immune evasion by Helicobacter pylori is mediated by induction of macrophage arginase II

ND Lewis, M Asim, DP Barry, T de Sablet… - The Journal of …, 2011 - journals.aai.org
Helicobacter pylori infection persists for the life of the host due to the failure of the immune
response to eradicate the bacterium. Determining how H. pylori escapes the immune …

Polyamines impair immunity to Helicobacter pylori by inhibiting L-arginine uptake required for nitric oxide production

R Chaturvedi, M Asim, S Hoge, ND Lewis, K Singh… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Helicobacter pylori–induced immune responses fail to eradicate
the bacterium. Nitric oxide (NO) can kill H pylori. However, translation of inducible NO …

RNA sequencing of microglia and monocyte-derived macrophages from mice with experimental autoimmune encephalomyelitis illustrates a changing phenotype with …

ND Lewis, JD Hill, KW Juchem… - Journal of …, 2014 - Elsevier
The role of microglia and monocyte-derived macrophages in experimental autoimmune
encephalomyelitis pathogenesis has been controversial. To gain insight into their respective …

Exosome surface display of IL12 results in tumor-retained pharmacology with superior potency and limited systemic exposure compared with recombinant IL12

ND Lewis, CL Sia, K Kirwin, S Haupt, G Mahimkar… - Molecular cancer …, 2021 - AACR
ND Lewis reports personal fees, nonfinancial support, and other from Codiak BioSciences …
outside the submitted work; in addition, ND Lewis has a patent for US10723782B2 issued. CL …

Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection

…, T Murray-Stewart, RA Casero, T Verriere, ND Lewis… - Amino acids, 2016 - Springer
We reported that arginase 2 (ARG2) deletion results in increased gastritis and decreased
bacterial burden during Helicobacter pylori infection in mice. Our studies implicated a potential …