Functions of lncRNA in development and diseases

EL Mathieu, M Belhocine, LT Dao, D Puthier… - … Sciences: M/S, 2014 - europepmc.org
The transcription of essentially the entire eukaryotic genome generates a myriad of non-coding
RNA species that show complex overlapping patterns of expression and regulation. In …

[HTML][HTML] Exocytotic insertion of TRPC6 channel into the plasma membrane upon Gq protein-coupled receptor activation

S Cayouette, MP Lussier, EL Mathieu… - Journal of Biological …, 2004 - ASBMB
TRPC proteins are the mammalian homologues of the Drosophila transient receptor potential
channel and are involved in calcium entry after agonist stimulation of non-excitable cells. …

Dynamics of broad H3K4me3 domains uncover an epigenetic switch between cell identity and cancer-related genes

…, I Manosalva, L Pradel, C Smith, EL Mathieu… - Genome …, 2022 - genome.cshlp.org
Broad domains of H3K4 methylation have been associated with consistent expression of
tissue-specific, cell identity, and tumor suppressor genes. Here, we identified broad domain–…

Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation

…, G Charbonnier, M Tesio, EL Mathieu… - Journal of Experimental …, 2020 - rupress.org
Cell differentiation is accompanied by epigenetic changes leading to precise lineage
definition and cell identity. Here we present a comprehensive resource of epigenomic data of …

ATP/UTP activate cation-permeable channels with TRPC3/7 properties in rat cardiomyocytes

…, JM Rauzier, J Magyar, EL Mathieu… - American Journal …, 2008 - journals.physiology.org
Extracellular purines and pyrimidines have major effects on cardiac rhythm and contraction.
ATP/UTP are released during various physiopathological conditions, such as ischemia, and …

[HTML][HTML] LINT, a novel dL (3) mbt-containing complex, represses malignant brain tumour signature genes

K Meier, EL Mathieu, F Finkernagel, LM Reuter… - PLoS …, 2012 - journals.plos.org
Mutations in the l(3)mbt tumour suppressor result in overproliferation of Drosophila larval
brains. Recently, the derepression of different gene classes in l(3)mbt mutants was shown to be …

[HTML][HTML] Low level CpG island promoter methylation predicts a poor outcome in adult T-cell acute lymphoblastic leukemia

…, C Graux, M Latiri, L Lhermitte, EL Mathieu… - …, 2020 - ncbi.nlm.nih.gov
Cancer cells undergo massive alterations in their DNA methylation patterns which result in
aberrant gene expression and malignant phenotypes. Abnormal DNA methylation is a …

Recruitment of the ATP-dependent chromatin remodeler dMi-2 to the transcribed region of active heat shock genes

EL Mathieu, F Finkernagel, M Murawska… - Nucleic acids …, 2012 - academic.oup.com
The ATP-dependent chromatin remodeler dMi-2 can play both positive and negative roles in
gene transcription. Recently, we have shown that dMi-2 is recruited to the hsp70 gene in a …

A comprehensive catalog of LncRNAs expressed in T-cell acute lymphoblastic leukemia

…, W Saadi, M Belhocine, EL Mathieu… - Leukemia & …, 2019 - Taylor & Francis
Several studies have demonstrated that LncRNAs can play major roles in cancer development.
The creation of a catalog of LncRNAs expressed in T cell acute lymphoblastic leukemia (…

[BOOK][B] Traité de physique mathématique: Cours de physique mathématique. 5

ÉL Mathieu - 1888 - books.google.com
Mathieu, qui pourrait être intitulée Prodrome de Mécanique céleste. On peut citer deux …
Mathieu ait utilisé tous les résultats acquis à la Science dans cette branche des Mathématiques, c'…