Microglia are associated with central nervous system (CNS) pathology of both Alzheimer's
disease (AD) and the acquired immunodeficiency syndrome (AIDS). In AD, microglia, …

Recent studies of gliosis in a variety of animal models are reviewed. The models include
brain injury, neurotoxic damage, genetic diseases and inflammatory demyelination. These …

… (c) Modular global transcriptional repression occurs under heat shock conditions in
human cell lines. Under heat shock, Pol III drives the expression of the Alu ncRNA from SINE …

… ), three times at 65C with buffer, twice at 65C with buffer diluted 1:2, and once at 65C with
buffer diluted 15. Exposure to X-ray film was performed at -7O"C, with intensifying screens. …

… fixed in acetone for 10 min at 4C. After blocking with 0.03% hydrogen peroxide and serum,
the sections were incubated with primary antibody overnight at 4C at the appropriate dilution. …

… They were then shaken at 200 rpm for 20 rnin at 37C. The nonadherent oligodendrocytes
were removed and plated on PLL coated 24- or 96-well plates at a concentration of 5 x lo5 cells…

During mammalian central nervous system (CNS) development, contact-mediated activation
of Notch1 receptors on oligodendrocyte precursors by the ligand Jagged1 induces Hes5, …

… Spinal cord astrocytes plated on MatTek dishes were loaded with fura-2 AM (10 μm) for
45 min at 37C and changes in fura-2 fluorescence intensities measured as described above. …

… mM DTT for 10 min at 45C. Sections were then incubated in … with probe for 18 h at 45C.
Sections were washed with 2× SSC … in 2× SSC at 55C and once in 0.1× SSC at 70C for 15 min. …

Nitric oxide generated by the inducible form of nitric oxide synthase (iNOS) may contribute to
the pathogenesis of multiple sclerosis (MS). In this report, we studied postmortem tissues of …