Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells

…, EK Parkinson, C Paraskeva, WN Keith, MC Frame - Oncogene, 1999 - nature.com
Focal adhesion kinase (pp125 FAK) is present at sites of cell/extracellular matrix adhesion
and has been implicated in the control of cell behaviour. In particular, as a key component of …

Calpain 2 and Src dependence distinguishes mesenchymal and amoeboid modes of tumour cell invasion: a link to integrin function

…, TK Sawyer, VG Brunton, BW Ozanne, MC Frame - Oncogene, 2006 - nature.com
… MC Frame … The X axis represents sequential time frames collected every 30 min. Each
line represents an individual cell tracked within the three-dimensional matrix. … MC Frame

Src kinase modulates the activation, transport and signalling dynamics of fibroblast growth factor receptors

…, A Vecchione, DG McEwan, MC Frame… - EMBO …, 2007 - embopress.org
The non‐receptor tyrosine kinase Src is recruited to activated fibroblast growth factor receptor
(FGFR) complexes through the adaptor protein factor receptor substrate 2 (FRS2). Here, …

Low-dose cidofovir treatment of BK virus-associated hemorrhagic cystitis in recipients of hematopoietic stem cell transplant

MR Savona, D Newton, D Frame, JE Levine… - Bone marrow …, 2007 - nature.com
In recipients of hematopoietic stem cell transplants (HSCTs), BK virus (BKV) has been
associated with late-onset hemorrhagic cystitis (HC). In our institution, HSCT recipients with BKV-…

A role for epidermal growth factor receptor, c-Src and focal adhesion kinase in an in vitro model for the progression of colon cancer

VG Brunton, BW Ozanne, C Paraskeva, MC Frame - Oncogene, 1997 - nature.com
We have examined the function of the epidermal growth factor (EGF) receptor, c-Src and
focal adhesion kinase (FAK) in the progression of colon cancer using an in vitro progression …

Flow cytometric analysis of normal B cell differentiation: a frame of reference for the detection of minimal residual disease in precursor-B-ALL

P Lucio, A Parreira, MWM Van den Beemd… - Leukemia, 1999 - nature.com
… The phenotypic profiles in normal B cell differentiation may form a frame of reference for the
… Our major goal was to investigate the BM B cell compartment in order to generate a frame of …

[PDF][PDF] Distinct sources of hematopoietic progenitors emerge before HSCs and provide functional blood cells in the mammalian embryo

…, JM Frame, KH Fegan, JR Bowen, SJ Conway… - Cell reports, 2015 - cell.com
Hematopoietic potential arises in mammalian embryos before adult-repopulating hematopoietic
stem cells (HSCs). At embryonic day 9.5 (E9.5), we show the first murine definitive …

[HTML][HTML] Active ERK/MAP kinase is targeted to newly forming cell–matrix adhesions by integrin engagement and v‐Src

VJ Fincham, M James, MC Frame, SJ Winder - The EMBO journal, 2000 - embopress.org
Integrin engagement generates cellular signals leading to the recruitment of structural and
signalling molecules which, in concert with rearrangements of the actin cytoskeleton, leads to …

[HTML][HTML] Elevated c-Src is linked to altered cell–matrix adhesion rather than proliferation in KM12C human colorectal cancer cells

…, AW Wyke, DW Owens, VG Brunton, MC Frame - British journal of …, 2002 - nature.com
Elevated expression and/or activity of c-Src, the prototype of the Src family of protein tyrosine
kinases, is associated with the development of human colon cancer. However, despite the …

Motion compensated frame rate up-conversion using extended bilateral motion estimation

SJ Kang, KR Cho, YH Kim - IEEE Transactions on Consumer …, 2007 - ieeexplore.ieee.org
frame rate moving image from the one with a lower frame rate through the process of generating
new frames … [4] BD Choi, JW Han, CS Kim, and SJ Ko, "Frame rate upconversion using …