User profiles for R. Dubois

Raymond DuBois

The Medical University of South Carolina
Verified email at musc.edu
Cited by 70331

Cyclooxygenase in biology and disease

RN Dubois, SB Abramson, L Crofford… - The FASEB …, 1998 - Wiley Online Library
Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to
prostaglandins was first identified over 20 years ago. Drugs, like aspirin, that inhibit …

The role of cyclooxygenases in inflammation, cancer, and development

CS Williams, M Mann, RN DuBois - Oncogene, 1999 - nature.com
The cyclooxygenase (COX) enzymes catalyze a key step in the conversion of arachidonate
to PGH 2, the immediate substrate for a series of cell specific prostaglandin and …

Eicosanoids and cancer

D Wang, RN DuBois - Nature Reviews Cancer, 2010 - nature.com
Eicosanoids, including prostaglandins and leukotrienes, are biologically active lipids that
have been implicated in various pathological processes, such as inflammation and cancer. …

The large area telescope on the Fermi gamma-ray space telescope mission

…, SW Digel, EC e Silva, PS Drell, R Dubois… - The Astrophysical …, 2009 - iopscience.iop.org
… Ciprini 17,18 , R. Claus 3 , J. Cohen-Tanugi 29 , S. … Dubois 3 , D. Dumora 34,35 , Y.
Edmonds 3 , D. … Rainò 19,20 , R. Rando 11,12 , E. Rapposelli 5 , M. …

LSST: from science drivers to reference design and anticipated data products

…, R Dubois, GP Dubois-Felsmann… - The Astrophysical …, 2019 - iopscience.iop.org
Major advances in our understanding of the universe have historically arisen from dramatic
improvements in our ability to “see.” We have developed progressively larger telescopes …

[HTML][HTML] Cyclooxygenase regulates angiogenesis induced by colon cancer cells

…, S Kawano, S Tsuji, H Sawaoka, M Hori, RN DuBois - cell, 1998 - cell.com
To explore the role of cyclooxygenase (COX) in endothelial cell migration and angiogenesis,
we have used two in vitro model systems involving coculture of endothelial cells with colon …

Fermi large area telescope third source catalog

…, L Di Venere, PS Drell, R Dubois… - The Astrophysical …, 2015 - iopscience.iop.org
We present the third Fermi Large Area Telescope (LAT) source catalog (3FGL) of sources in
the 100 MeV–300 GeV range. Based on the first 4 yr of science data from the Fermi Gamma-…

Fermi large area telescope second source catalog

…, PS Drell, A Drlica-Wagner, R Dubois… - The Astrophysical …, 2012 - iopscience.iop.org
This paper presents a catalog of high-energy γ-ray sources detected in the first two years of
the Fermi Gamma-ray Space Telescope mission by the Large Area Telescope (LAT). It is the …

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

…, A Radhika, FM Giardiello, S Ferrenbach, RN Dubois - Gastroenterology, 1994 - Elsevier
Background/Aims: Several clinical, epidemiological, and animal studies indicate that nonsteroidal
anti-inflammatory drugs (NSAIDs) may alter the incidence of colorectal cancer. A likely …

Fermi large area telescope first source catalog

…, EC e Silva, PS Drell, R Dubois… - The Astrophysical …, 2010 - iopscience.iop.org
We present a catalog of high-energy gamma-ray sources detected by the Large Area Telescope
(LAT), the primary science instrument on the Fermi Gamma-ray Space Telescope (Fermi…