Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome)

M Zenker, J Mayerle, MM Lerch, A Tagariello… - Nature …, 2005 - nature.com
… -Blizzard syndrome. UBR1 encodes one of at least four functionally overlapping E3 ubiquitin
ligases of the N-end … N-terminal residues 2,3,4,5 . Pancreas of individuals with Johanson-…

Eponym: Johanson-Blizzard syndrome

N Rezaei, M Sabbaghian, Z Liu, M Zenker - European journal of pediatrics, 2011 - Springer
… The gene encodes one of the E3 ubiquitin ligases of the N-end rule pathway, which targets
proteins to proteasomal degradation depending on the identity of their N-terminal residue. …

Investigating the potential role of North American animals as hosts for Zika virus

IK Ragan, EL Blizzard, P Gordy… - Vector-Borne and …, 2017 - liebertpub.com
The recent emergence of the mosquito-borne Zika virus (ZIKV) in the Americas has become
a global public health concern. We describe a series of experimental infections designed to …

[HTML][HTML] Ubiquitin Ligases of the N-End Rule Pathway: Assessment of Mutations in UBR1 That Cause the Johanson-Blizzard Syndrome

CS Hwang, M Sukalo, O Batygin, MC Addor… - PLoS …, 2011 - journals.plos.org
Background Johanson-Blizzard syndrome (JBS; OMIM 243800) is an autosomal recessive
disorder that includes congenital exocrine pancreatic insufficiency, facial dysmorphism with …

[HTML][HTML] An updated blizzard climatology of the contiguous United States (1959–2014): An examination of spatiotemporal trends

JSM Coleman, RM Schwartz - Journal of Applied Meteorology …, 2017 - journals.ametsoc.org
… Stanglin, 2016: Epic blizzard with heavy snow begins to move up East Coast. USA Today,
23 January, accessed 23 August 2016. [Available online at http://www.usatoday.com/story/…

Two types of autoimmune Addison's disease associated with different polyglandular autoimmune (PGA) syndromes

M Neufeld, NK Maclaren, RM Blizzard - Medicine, 1981 - journals.lww.com
Autoimmune Addison's disease has been de-scribed in association with acquired
hypoparathyroidism, chronic mucocutaneous candidiasis, insulin requiring diabetes mellitus, …

What's buzzing in the blizzard of buzz? Automotive component isolation in social media postings

AS Abrahams, J Jiao, W Fan, GA Wang… - Decision Support …, 2013 - Elsevier
… Detecting “whispers of useful information in a howling hurricane of noise” is a huge challenge
and filters are needed to extract meaning from the “blizzard of buzz”, prompting automotive …

[HTML][HTML] Skipping breakfast: longitudinal associations with cardiometabolic risk factors in the Childhood Determinants of Adult Health Study

KJ Smith, SL Gall, SA McNaughton, L Blizzard… - The American journal of …, 2010 - Elsevier
… nor adulthood (n = 1359), skipped breakfast only in childhood (n = 224), skipped breakfast
only in adulthood (n = 515), and skipped breakfast in both childhood and adulthood (n = 86). …

Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712

H Chen, TA Blizzard, S Kim, J Wu, K Young… - Bioorganic & medicinal …, 2011 - Elsevier
… In the search for a backup for 1, we synthesized and report herein numerous N-substituted
and open chain analogs. The N-methyl (2) and N,N-dimethyl (3) analogs were prepared from …

[BOOK][B] The Children's Blizzard

D Laskin - 2009 - books.google.com
… aOn January 12, 1888, a blizzard broke over the center of the North American continent. Out
of … Montana fell before dawn; North Dakota went while farmers were out doing their early …