Foot-and-mouth disease

MJ Grubman, B Baxt - Clinical microbiology reviews, 2004 - Am Soc Microbiol
… This protein is related to the trypsin family of serine proteases (18, 45, 179), and Grubman
and coworkers have mapped the active site of FMDV 3C pro to Cys163, His46, and Asp84 (…

Molecular basis of pathogenesis of FMDV

PW Mason, MJ Grubman, B Baxt - Virus research, 2003 - Elsevier
Current understanding of the molecular basis of pathogenesis of foot-and-mouth disease (FMD)
has been achieved through over 100 years of study into the biology of the etiologic agent…

Foot and mouth disease virus vaccines

LL Rodriguez, MJ Grubman - Vaccine, 2009 - Elsevier
Foot and mouth disease (FMD) is a highly infectious and economically devastating disease
of livestock. Although vaccines, available since the early 1900s, have been instrumental in …

[HTML][HTML] Endometrial findings among transgender and gender nonbinary people using testosterone at the time of gender-affirming hysterectomy

…, MB Deutsch, J Obedin-Maliver, B Stark, J Grubman… - Fertility and sterility, 2021 - Elsevier
Objective To describe clinical characteristics and associated endometrial findings of
transgender and gender nonbinary people using gender-affirming testosterone. Design …

Cloned viral protein vaccine for foot-and-mouth disease: responses in cattle and swine

…, B Small, D Dowbenko, DM Moore, MJ Grubman… - Science, 1981 - science.org
A DNA sequence coding for the immunogenic capsid protein VP 3 of foot-and-mouth disease
virus A 12 , prepared from the virion RNA, was ligated to a plasmid designed to express a …

Leader protein of foot-and-mouth disease virus is required for cleavage of the p220 component of the cap-binding protein complex

…, RE Lloyd, E Ehrenfeld, MJ Grubman - Journal of …, 1988 - Am Soc Microbiol
… FMDV, like poliovirus, very rapidly and efficiently inhibits host cell protein synthesis (6; MJ
Grubman, … We thank John J. Dunn for the gift of T7 RNA polymerase and Mary A. Wigmore for …

Nitrous oxide self-administration by the squirrel monkey.

RW Wood, J Grubman, B Weiss - The Journal of Pharmacology and …, 1977 - psycnet.apa.org
Four female squirrel monkeys self-administered nitrous oxide (N₂O) by pressing a key that
introduced N₂O into the flow of gas through a helmet placed over the head. This behavior …

Inhibition of L-deleted foot-and-mouth disease virus replication by alpha/beta interferon involves double-stranded RNA-dependent protein kinase

J Chinsangaram, M Koster, MJ Grubman - Journal of virology, 2001 - Am Soc Microbiol
We previously demonstrated that the ability of foot-and-mouth disease virus (FMDV) to form
plaques in cell culture is associated with the suppression of alpha/beta interferon (IFN-α/β). …

The pathogenesis of foot‐and‐mouth disease II: viral pathways in swine, small ruminants, and wildlife; myotropism, chronic syndromes, and molecular virus–host …

J Arzt, B Baxt, MJ Grubman, T Jackson… - Transboundary and …, 2011 - Wiley Online Library
Investigation into the pathogenesis of foot‐and‐mouth disease (FMD) has focused on the
study of the disease in cattle with less emphasis on pigs, small ruminants and wildlife. ‘Atypical…

The leader proteinase of foot-and-mouth disease virus inhibits the induction of beta interferon mRNA and blocks the host innate immune response

…, S de Avila Botton, R Weiblen, MJ Grubman - Journal of …, 2006 - Am Soc Microbiol
We have previously shown that the leader proteinase (L pro ) of foot-and-mouth disease virus
(FMDV) blocks cap-dependent mRNA translation and that a genetically engineered FMDV …